Best Piles & Fistula Treatment in Jaipur Dr Manish Rajput
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Get the best piles and fistula treatment in Jaipur with advanced laser proctology techniques. Dr. Manish Rajput, a renowned specialist, provides painless, quick, and highly effective treatments for piles, fissures, and fistula. Using cutting-edge laser technology, the procedures ensure minimal discomfort, no stitches, and faster recovery, helping patients return to their daily lives with ease. Dr. Rajput is committed to offering personalized care and long-term solutions, ensuring lasting relief and improved quality of life. With his expertise and modern facilities, you can expect safe and reliable treatment for all proctological conditions.
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TOBACCO (nicotina tabbacum)-the Tobacco: A Global Perspective harmbiswalamandeep Tobacco refers to the plant Nicotiana tabacum and the cured leaves used for smoking, chewing, or snuffing, containing the highly addictive substance nicotine.
Neurotransmitters by dr k ambareesha PhD
Neurotransmitters by dr k ambareesha PhDDr K Ambareesha Goud PhD Neurotransmitters are chemical messengers that transmit signals between nerve cells (neurons) and other cells, playing a crucial role in various bodily functions, including motor control, perception, and cognitive processes
A Roadmap for Managing Post-HCT VOD/SOS: Team-Based Guidance on Capturing, As...
A Roadmap for Managing Post-HCT VOD/SOS: Team-Based Guidance on Capturing, As...PVI, PeerView Institute for Medical Education Co-Chairs, Prof. Dr. Selim Corbacioglu and Christine N. Duncan, MD, discuss hepatic veno-occlusive disease in this CME/NCPD activity titled “A Roadmap for Managing Post-HCT VOD/SOS: Team-Based Guidance on Capturing, Assessing, and Managing Diverse Presentations.” For the full presentation, downloadable Practice Aids, and complete CME/NCPD information, and to apply for credit, please visit us at https://bit.ly/4fbOeNt. CME/NCPD credit will be available until April 19, 2026.
UNIT 5TH PHARMACEUTICS SEMI SOLID DOSAGE FORM PPT
UNIT 5TH PHARMACEUTICS SEMI SOLID DOSAGE FORM PPTAnkitVishwakarma84 BACHELOR OF PHARMACY PHARMACEUTICS UNIT 5TH SEMI SOLID DOSAGE FORMS
Ethics in Clinical Research Regulation including historical perspective for (...
Ethics in Clinical Research Regulation including historical perspective for (...Om Mahajan MRA - 103T, Unit -2, This is best of content you can find.
Parasympathomimetics or Cholinergic Drugs By Baasir Umair
Parasympathomimetics or Cholinergic Drugs By Baasir UmairBaasir Umair Khattak Parasympathomimetics: Mechanism, Effects, and Clinical Applications
Parasympathomimetics, also known as cholinergic agonists, are drugs that mimic the actions of the parasympathetic nervous system (PNS). The PNS is responsible for the "rest and digest" functions in the body, and parasympathomimetic drugs act primarily by stimulating cholinergic receptors. This document explores the various aspects of parasympathomimetics, including their classification, mechanism of action, physiological effects, clinical applications, and potential side effects.
1. Introduction to Parasympathomimetics
Parasympathomimetic drugs enhance the effects of acetylcholine (ACh), the primary neurotransmitter of the parasympathetic nervous system. These agents can either directly stimulate cholinergic receptors or indirectly increase acetylcholine levels.
2. Classification of Parasympathomimetics
Parasympathomimetics are categorized into two main types based on their mode of action:
Direct-acting parasympathomimetics: These drugs bind directly to muscarinic or nicotinic receptors, mimicking the action of acetylcholine. Examples include pilocarpine and bethanechol.
Indirect-acting parasympathomimetics: These inhibit acetylcholinesterase (AChE), the enzyme that breaks down acetylcholine, thereby increasing its availability. Examples include neostigmine, physostigmine, and donepezil.
3. Mechanism of Action
Direct-acting agents: Bind to muscarinic or nicotinic receptors, leading to stimulation of parasympathetic responses such as increased glandular secretion, smooth muscle contraction, and decreased heart rate.
Indirect-acting agents: Inhibit acetylcholinesterase, preventing acetylcholine breakdown and prolonging its action at synapses.
4. Physiological Effects
Parasympathomimetics produce a range of effects across different organ systems:
Cardiovascular system: Decrease heart rate (bradycardia) and lower blood pressure by vasodilation.
Respiratory system: Increase bronchoconstriction and mucus secretion.
Gastrointestinal system: Enhance peristalsis, increase secretion of digestive enzymes, and promote bowel movements.
Urinary system: Stimulate bladder contraction, aiding in urine excretion.
Ocular effects: Induce pupil constriction (miosis) and facilitate aqueous humor drainage, useful in glaucoma treatment.
Neurological effects: Improve cognitive function in neurodegenerative diseases like Alzheimer’s.
5. Clinical Applications
Glaucoma treatment: Pilocarpine reduces intraocular pressure by improving aqueous humor drainage.
Urinary retention: Bethanechol stimulates bladder contraction to relieve urinary retention.
Myasthenia gravis: Neostigmine and pyridostigmine improve neuromuscular transmission.
Alzheimer’s disease: Donepezil and rivastigmine enhance cholinergic function in the brain.
Reversal of neuromuscular blockade: Neostigmine is used post-surgery to restore muscle function.
Xerostomia (dry mouth): Pilocarpine enhances salivation in patients
Maximizing Therapeutic Innovations in Bladder Cancer: Expert Strategies for C...
Maximizing Therapeutic Innovations in Bladder Cancer: Expert Strategies for C...PVI, PeerView Institute for Medical Education Chair, Andrea Necchi, MD, Sia Daneshmand, MD, and Shilpa Gupta, MD, discuss bladder cancer in this CME/MOC/AAPA/IPCE activity titled “Maximizing Therapeutic Innovations in Bladder Cancer: Expert Strategies for Comprehensive Care Across Disease Stages.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/422z9Kf. CME/MOC/AAPA/IPCE credit will be available until March 14, 2026.
Quality management system regulation (QMSR )Final rule 2024
Quality management system regulation (QMSR )Final rule 2024vishwas16691 QMSR Final Rule 2024 aligns 21 CFR Part 820 with ISO 13485:2016—discover key updates and insights for medical devices in my PPT!
iatrogenic damages of ortho treatment - sunitha.ppt
iatrogenic damages of ortho treatment - sunitha.pptPseudoPocket iatrogenic damages of ortho treatment - sunitha.ppt
Classification and Properties of Nerve Fibre.pptx
Classification and Properties of Nerve Fibre.pptxPranaliChandurkar2 A nerve fibre, also called an axon, is a long and slender projection of nerve cells (or neurons) that carry electrical impulses away from the nerve cell body.
A neuron typically has one nerve fibre emanating from its cell body that transmits impulses to other neurons, muscles or glands.
Dysfunctioning of the nerve fibre can cause major acquired and inherited neurological disorders that affect both the central nervous system and the peripheral nervous system.
Physiological Properties of Nerve Fibres
Excitability: The nerve fibres are highly excitable structures that respond to several stimuli and can also generate electrical impulses.
Conductivity: The electrical impulses generated in the nerve fibres are propagated along its entire length and to different neurons, muscles and glands by synaptic connections.
Refractory Period: The nerve fibres can conduct one action potential at once, i.e., the excitability of the fibres is less during conduction and hence a new electrical impulse cannot be generated.
All or None Response: A nerve fiber translates either all of the impulse or none at all. If a stimulus is applied upto a threshold level, an action potential will be generated but increasing the strength of the stimulus will not affect the action potential.
Summation: If a sub-threshold stimulus is applied, it cannot generate an action potential. However, when multiple sub-threshold stimuli are applied in rapid succession, an action potential is generated.
Classification of Nerve Fibers
Nerve fibers are classified based on
Structure (myelinated/unmyelinated)
Distribution (somatic/autonomic)
Origin (cranial/spinal)
Function (sensory/motor)
Diameter/impulse conduction (A, B, C fibers).
They exhibit properties like excitability, conductivity, and the ability to transmit signals via electrical and chemical pathways.
Case representation of kidney disease and uremic Encephalopathy .pptx
Case representation of kidney disease and uremic Encephalopathy .pptxPriyaKumari719835 This ppt contains a real case of a chronic kidney disease and uremic Encephalopathy patient from the hospital S N medical College Agra
Regulatory Framework for Drug Import Under the Drugs and Cosmetics Act, 1940 ...
Regulatory Framework for Drug Import Under the Drugs and Cosmetics Act, 1940 ...Dr.Navaneethakrishnan S This presentation provides an in-depth overview of drug import regulations under the Drugs and Cosmetics Act, 1940, and its Rules, 1945. It covers key topics such as prohibited imports, import of new drugs, personal use import regulations, import licensing requirements, and storage conditions for scheduled drugs. It also explains government restrictions, exemptions, and penalties for violations. This guide is essential for pharmacy students, regulatory professionals, and individuals involved in the import and distribution of pharmaceutical products in India.
Detailed Overview of the Drugs and Cosmetics Act, 1940 & Rules
Detailed Overview of the Drugs and Cosmetics Act, 1940 & RulesDr.Navaneethakrishnan S This presentation provides a comprehensive overview of the Drugs and Cosmetics Act, 1940, and its associated rules from 1945. It covers the objectives of the Act, its significance in regulating the import, manufacture, distribution, and sale of drugs and cosmetics in India. Key definitions such as drugs, cosmetics, misbranded, adulterated, and spurious products are explained in detail. Additionally, it highlights the legal definitions and important schedules to the Act, ensuring clarity on regulatory standards. Essential roles such as Drug Inspector and Government Analyst are also discussed. This presentation is useful for pharmacy students, regulatory professionals, and individuals interested in pharmaceutical law.
Title: 📊 Pharmacoeconomics: History, Principles, Methods, and Applications
Title: 📊 Pharmacoeconomics: History, Principles, Methods, and Applicationssakshiaggarwal979034 📌 Description:
Pharmacoeconomics is a vital field that examines the economic impact of pharmaceutical products and healthcare services. This presentation provides a detailed overview of pharmacoeconomic principles, methodologies, and their significance in healthcare decision-making. It covers essential topics such as cost analysis, evaluation perspectives, and humanistic assessment methods.
💡 Key Topics Covered:
✔ History and Evolution of Pharmacoeconomics
✔ Goals and Objectives of Pharmacoeconomic Studies
✔ Cost Analysis & Consequences (Outcomes)
✔ Different Pharmacoeconomic Methodologies (Cost-Minimization, Cost-Effectiveness, Cost-Utility, Cost-Benefit)
✔ Perspectives in Economic Evaluations (Payer, Patient, Society)
✔ Role of Pharmacoeconomics in Drug Safety & Pharmacovigilance
✔ Humanistic Evaluation Methods (Quality of Life & Patient-Reported Outcomes)
✔ Importance of Pharmacoeconomics in Policy & Healthcare Decisions
MASTERING FLAPS IN ORAL & MAXILLOFACIAL SURGERY
MASTERING FLAPS IN ORAL & MAXILLOFACIAL SURGERYhriday20 THE ART & SCIENCE OF FLAPS IN ORAL SURGERY : UNLOCKING PRECISION IN HEALING
Flap techniques are essential in oral surgery , directly impacting recovery and success . In this presentation , we will dive into the basics of flap design and its crucial role in achieving optimal outcomes. Ready to enhance your surgical skills?
Lets explore the art of flaps together.
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A Roadmap for Managing Post-HCT VOD/SOS: Team-Based Guidance on Capturing, As...
A Roadmap for Managing Post-HCT VOD/SOS: Team-Based Guidance on Capturing, As...PVI, PeerView Institute for Medical Education
Maximizing Therapeutic Innovations in Bladder Cancer: Expert Strategies for C...
Maximizing Therapeutic Innovations in Bladder Cancer: Expert Strategies for C...PVI, PeerView Institute for Medical Education
Regulatory Framework for Drug Import Under the Drugs and Cosmetics Act, 1940 ...
Regulatory Framework for Drug Import Under the Drugs and Cosmetics Act, 1940 ...Dr.Navaneethakrishnan S